BDBM808022 N-(4-((2-((3-(2-(4- cyclopropylpiperazin-1- yl)ethyl)phenyl)amino)pyrimidin- 4-yl)oxy)-3-fluorophenyl)-1-(4- fluorophenyl)-5- (trifluoromethyl)-1H-pyrazole-4- carboxamide::US20260132158, Example 49

SMILES O=C(Nc1ccc(Oc2ccnc(Nc3cccc(CCN4CCN(C5CC5)CC4)c3)n2)c(F)c1)c1cnn(-c2ccc(F)cc2)c1C(F)(F)F

InChI Key InChIKey=HURGPTGXHFZSCH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 808022   

TargetMacrophage-stimulating protein receptor(Human)
The Translational Genomics Research Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 808022BDBM808022(N-(4-((2-((3-(2-(4- cyclopropylpiperazin-1- yl)eth...)
Affinity DataIC50: 1.00E+3nMAssay Description:Kinase assay was done by following instructions from the kit. Briefly, a ten-point serial dilution of compound was prepared at 5× in assay buffer wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
The Translational Genomics Research Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 808022BDBM808022(N-(4-((2-((3-(2-(4- cyclopropylpiperazin-1- yl)eth...)
Affinity DataIC50: 1.00E+3nMAssay Description:Kinase assay was done by following instructions from the kit. Briefly, a ten point serial dilution of compound was prepared at 5× in assay buffer wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent