BDBM808439 N-(4-(6-methoxy-7- (2-(4- methylpiperazin-1- yl)ethoxy)quinazolin- 4-yl)phenyl)-2-(4- (trifluoromethyl) phenyl)acetamide::US20260138959, Example 3

SMILES COc1cc2c(-c3ccc(NC(=O)Cc4ccc(C(F)(F)F)cc4)cc3)ncnc2cc1OCCN1CCN(C)CC1

InChI Key InChIKey=ZGTVJNBAWAWEHI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 808439   

TargetPlatelet-derived growth factor receptor beta(Human)
Voronoi

US Patent
LigandChemical structure of BindingDB Monomer ID 808439BDBM808439(N-(4-(6-methoxy-7- (2-(4- methylpiperazin-1- yl)et...)
Affinity DataIC50: 50nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor alpha(Human)
Voronoi

US Patent
LigandChemical structure of BindingDB Monomer ID 808439BDBM808439(N-(4-(6-methoxy-7- (2-(4- methylpiperazin-1- yl)et...)
Affinity DataIC50: 50nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 808439BDBM808439(N-(4-(6-methoxy-7- (2-(4- methylpiperazin-1- yl)et...)
Affinity DataIC50: 50nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit(Human)
Voronoi

US Patent
LigandChemical structure of BindingDB Monomer ID 808439BDBM808439(N-(4-(6-methoxy-7- (2-(4- methylpiperazin-1- yl)et...)
Affinity DataIC50: 50nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent