BDBM808493 N-(4-(6-(2-(di- ethylamino)- ethoxy)-7-meth- oxyquinazolin- 4-yl)phenyl)-2- (4-fluorophen- yl)acetamide::US20260138959, Example 122

SMILES CCN(CC)CCOc1cc2c(-c3ccc(NC(=O)Cc4ccc(F)cc4)cc3)ncnc2cc1OC

InChI Key InChIKey=LQUMKKJWYDRNDP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 808493   

TargetPlatelet-derived growth factor receptor alpha(Human)
Voronoi

US Patent
LigandChemical structure of BindingDB Monomer ID 808493BDBM808493(N-(4-(6-(2-(di- ethylamino)- ethoxy)-7-meth- oxyqu...)
Affinity DataIC50: 50nMAssay Description:In order to evaluate the inhibitory activity of the compounds synthesized according to the above examples on PDGFR-α(wt), PDGFR-β(wt), c-KIT(wt), and...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit(Human)
Voronoi

US Patent
LigandChemical structure of BindingDB Monomer ID 808493BDBM808493(N-(4-(6-(2-(di- ethylamino)- ethoxy)-7-meth- oxyqu...)
Affinity DataIC50: 50nMAssay Description:In order to evaluate the inhibitory activity of the compounds synthesized according to the above examples on PDGFR-α(wt), PDGFR-β(wt), c-KIT(wt), and...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 808493BDBM808493(N-(4-(6-(2-(di- ethylamino)- ethoxy)-7-meth- oxyqu...)
Affinity DataIC50: 50nMAssay Description:In order to evaluate the inhibitory activity of the compounds synthesized according to the above examples on PDGFR-α(wt), PDGFR-β(wt), c-KIT(wt), and...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor beta(Human)
Voronoi

US Patent
LigandChemical structure of BindingDB Monomer ID 808493BDBM808493(N-(4-(6-(2-(di- ethylamino)- ethoxy)-7-meth- oxyqu...)
Affinity DataIC50: 75nMAssay Description:In order to evaluate the inhibitory activity of the compounds synthesized according to the above examples on PDGFR-α(wt), PDGFR-β(wt), c-KIT(wt), and...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent