BDBM9343 (4R,5S,6S,7R)-4,7-dibenzyl-1-(cyclopropylmethyl)-5,6-dihydroxy-3-(naphthalen-2-ylmethyl)-1,3-diazepan-2-one::CHEMBL86959::Cyclic Urea 65

SMILES O[C@@H]1[C@@H](O)[C@@H](Cc2ccccc2)N(Cc2ccc3ccccc3c2)C(=O)N(CC2CC2)[C@@H]1Cc1ccccc1

InChI Key InChIKey=WIWOANAWRGKNSI-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 9343   

TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 9343BDBM9343(CHEMBL86959 | (4R,5S,6S,7R)-4,7-dibenzyl-1-(cyclop...)
Affinity DataKi:  1.5nMAssay Description:Ki values were determined with recombinant single-chain dimeric HIV protease and a fluorescent substrate. The use of single-chain dimeric protease a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2001
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Lindsley F. Kimball Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 9343BDBM9343(CHEMBL86959 | (4R,5S,6S,7R)-4,7-dibenzyl-1-(cyclop...)
Affinity DataKi:  1.5nMAssay Description:Inhibition of HIV-1 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed