BDBM50650888 PK-11195

SMILES CCC(C)N(C)C(=O)c1cc2ccccc2c(-c2ccccc2Cl)n1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50650888   

TargetNuclear receptor subfamily 1 group I member 3(Human)
Charles University

Curated by ChEMBL
LigandPNGBDBM50650888(PK-11195)
Affinity DataIC50: 25nMAssay Description:Antagonist activity at human CAR LBD (151 to 349 residues) expressed in HepG2 cells co-expressed with pGL5-luc luciferase assessed as reduction in CA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetNuclear receptor subfamily 1 group I member 3(Human)
Charles University

Curated by ChEMBL
LigandPNGBDBM50650888(PK-11195)
Affinity DataIC50: 245nMAssay Description:Inverse agonist activity at human CAR LBD (151 to 349 residues) expressed in HepG2 cells co-expressed with pGL5-luc luciferase assessed as reduction ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetNuclear receptor subfamily 1 group I member 3(Human)
Charles University

Curated by ChEMBL
LigandPNGBDBM50650888(PK-11195)
Affinity DataIC50: 6.98E+4nMAssay Description:Antagonist activity at human CAR LBD (151 to 349 residues) expressed in HepG2 cells co-expressed with pGL5-luc luciferase assessed as reduction in CA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed