BDBM50144841 (S)-1-(6-chloro-5-fluoro-1H-indol-1-yl)propan-2-amine::(S)-2-(6-Chloro-5-fluoro-indol-1-yl)-1-methyl-ethylamine::CHEMBL76781::Ro-60-0175::Ro-600175
SMILES C[C@H](N)Cn1ccc2cc(F)c(Cl)cc12
InChI Key InChIKey=XJJZQXUGLLXTHO-ZETCQYMHSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 23 hits for monomerid = 50144841
Affinity DataKi: 1.30nMAssay Description:Binding affinity against human 5-hydroxytryptamine 2C receptor using displacement of [3H]DOBMore data for this Ligand-Target Pair
Affinity DataKi: 2.30nMAssay Description:Affinity for human 5-hydroxytryptamine 2C receptor expressed in mammalian cell lineMore data for this Ligand-Target Pair
Affinity DataKi: 2.30nMAssay Description:Displacement of [3H]5HT from human 5HT2CMore data for this Ligand-Target Pair
Affinity DataKi: 5.10nMAssay Description:Affinity for human 5-hydroxytryptamine 2B receptor expressed in mammalian cell lineMore data for this Ligand-Target Pair
Affinity DataKi: 5.10nMAssay Description:Displacement of [3H]5HT from human 5HT2BMore data for this Ligand-Target Pair
Affinity DataKi: 26nMAssay Description:Displacement of [3H]5-HT from human 5HT2C receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 32nMAssay Description:Binding affinity against human 5-hydroxytryptamine 2A receptor using displacement of [3H]5-HTMore data for this Ligand-Target Pair
Affinity DataKi: 38nMAssay Description:Displacement of [125I]DOI from human 5HT2AMore data for this Ligand-Target Pair
Affinity DataKi: 38nMAssay Description:Functional activity against human 5-hydroxytryptamine 2C receptor expressed in CHO cells using fluorometricimaging plate readerMore data for this Ligand-Target Pair
Affinity DataKi: 39nMAssay Description:Displacement of [3H]5-HT from human 5HT2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 4nMAssay Description:Agonist activity at human 5HT2C receptor expressed in HEK293 cells assessed as intracellular IP3 accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: 1.60nMAssay Description:Agonist activity at human 5HT2B receptor expressed in HEK293 cells assessed as intracellular IP3 accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: 200nMAssay Description:Efficacy (pEC50) was evaluated for 5-HT2C receptor-mediated stimulation of IP3 formation in vitro in choroid plexus of the ratMore data for this Ligand-Target Pair
Affinity DataEC50: 2.40nMAssay Description:Agonist activity at human cloned 5HT2B receptor expressed in HEK293-EBNA cells assessed as myo-[3H]inositol hydrolysisMore data for this Ligand-Target Pair
Affinity DataEC50: 400nMAssay Description:Agonist activity at human cloned 5HT2A receptor expressed in CHO cells assessed as myo-[3H]inositol hydrolysisMore data for this Ligand-Target Pair
Affinity DataEC50: 52nMAssay Description:Agonist activity at human cloned 5HT2C receptor expressed in CHO cells assessed as myo-[3H]inositol hydrolysisMore data for this Ligand-Target Pair
Affinity DataEC50: 50nMAssay Description:Agonist activity at human 5HT2A receptor expressed in HEK293 cells assessed as intracellular IP3 accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: 18nMAssay Description:Binding to human 5HT2C receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 131nMAssay Description:Binding to human 5HT2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 4.30nMAssay Description:Functional activity against human 5-hydroxytryptamine 2B receptor expressed in CHO cells using fluorometricimaging plate readerMore data for this Ligand-Target Pair
Affinity DataEC50: 18nMAssay Description:Affinity for human 5-hydroxytryptamine 2B receptor expressed in mammalian cell lineMore data for this Ligand-Target Pair
Affinity DataEC50: 131nMAssay Description:Functional activity against human 5-hydroxytryptamine 2A receptor expressed in CHO cells using fluorometricimaging plate readerMore data for this Ligand-Target Pair
Affinity DataEC50: 4.30nMAssay Description:Binding to human 5HT2B receptor expressed in CHO cellsMore data for this Ligand-Target Pair