BDBM10236 5-chloro-2-cyclopropyl-13-{[(2,6-dimethylpyridin-4-yl)sulfanyl]methyl}-7-methyl-2,4,9,15-tetraazatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,12,14-hexaen-10-one::8-heteroarylthiomethyldipyridodiazepinone deriv. 18

SMILES Cc1cc(SCc2cnc3N(C4CC4)c4nc(Cl)cc(C)c4NC(=O)c3c2)cc(C)n1

InChI Key InChIKey=SNKPYTPMXOONSA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 10236   

TargetGag-Pol polyprotein [600-1027,K702N,Y780C]/[600-1155,K702N,Y780C](Human immunodeficiency virus type 1)
Boehringer Ingelheim (Canada)

LigandPNGBDBM10236(5-chloro-2-cyclopropyl-13-{[(2,6-dimethylpyridin-4...)
Affinity DataIC50:  280nMpH: 7.4 T: 2°CAssay Description:IC50 values for wild-type and mutant RTs were obtained from a scintillation proximity assay using poly rC/biotin-dG15 and 3H-dGTP. Each value represe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [600-1027,R876K]/[600-1155](Human immunodeficiency virus type 1)
Boehringer Ingelheim (Canada)

LigandPNGBDBM10236(5-chloro-2-cyclopropyl-13-{[(2,6-dimethylpyridin-4...)
Affinity DataIC50:  12nMpH: 7.4 T: 2°CAssay Description:IC50 values for wild-type and mutant RTs were obtained from a scintillation proximity assay using poly rC/biotin-dG15 and 3H-dGTP. Each value represe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed