BDBM102943 US8541427, 14
SMILES CN1C(N)=N[C@]2(CN(C[C@H]2C1=O)c1nc(C)c(F)c(n1)C1CC1)c1cccc(c1)C#N
InChI Key InChIKey=WBMPVZVSGVQMJZ-KSFYIVLOSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 102943
Affinity DataKi: 43nM ΔG°: -10.2kcal/mole IC50: 213nMT: 2°CAssay Description:A homogeneous time-resolved FRET assay was used to determine IC50 values for inhibitors of the soluble human BACE1 catalytic domain. The assay monit...More data for this Ligand-Target Pair