BDBM104068 (Z)-5-(4-(Cyclohexylthio)-3-nitrobenzylidene)-2-thioxothiazolidin-4- one 2::DNA polymerase inhibitor 2

SMILES [O-][N+](=O)c1cc(C=C2SC(S)=NC2=O)ccc1SC1CCCCC1

InChI Key InChIKey=SHSOLTGELRGKFN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 104068   

TargetDNA polymerase lambda(Homo sapiens (Human))
University of Konstanz

LigandPNGBDBM104068((Z)-5-(4-(Cyclohexylthio)-3-nitrobenzylidene)-2-th...)
Affinity DataIC50: <1.00E+4nMpH: 7.5Assay Description:Pol λ reactions were made in a final volume of 20uL containing 50mM Tris-HCl pH 7.5, 1.5mM MgCl2, 5% (v/v) glycerol, 1mM DTT, 250nM purified rec...More data for this Ligand-Target Pair
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TargetDNA polymerase beta(Homo sapiens (Human))
University of Konstanz

LigandPNGBDBM104068((Z)-5-(4-(Cyclohexylthio)-3-nitrobenzylidene)-2-th...)
Affinity DataIC50: <5.00E+4nMpH: 7.9Assay Description:Pol β reactions were made in a final volume of 20uL containing 50mM Tris-HCl pH 7.9, 20mM KCl, 5% (v/v) glycerol, 1mM DTT, 2mM MnCl2, 250nM puri...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed