BDBM104093 (Z)-5-(3-Bromo-4-((3-fluoro-4-methylphenyl)thio)benzylidene)-2- thioxothiazolidin-4-one 27::DNA polymerase inhibitor 27
SMILES Cc1ccc(Sc2ccc(C=C3SC(S)=NC3=O)cc2Br)cc1F
InChI Key InChIKey=JKZLCDFSFLJGCH-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 104093
Affinity DataIC50: 4.00E+3nMpH: 7.5Assay Description:Pol λ reactions were made in a final volume of 20uL containing 50mM Tris-HCl pH 7.5, 1.5mM MgCl2, 5% (v/v) glycerol, 1mM DTT, 250nM purified rec...More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMpH: 7.9Assay Description:Pol β reactions were made in a final volume of 20uL containing 50mM Tris-HCl pH 7.9, 20mM KCl, 5% (v/v) glycerol, 1mM DTT, 2mM MnCl2, 250nM puri...More data for this Ligand-Target Pair