BDBM104215 US8575145, 152::US8575145, 92::US8575145, 92/122

SMILES Cc1ccn2c(nnc2c1)-c1ccc2cccc(OC3CCNCCC3F)c2n1

InChI Key InChIKey=KOQXLXUOIGXSIW-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 104215   

TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM104215(US8575145, 152 | US8575145, 92 | US8575145, 92/122)
Affinity DataIC50:  17.5nMAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM104215(US8575145, 152 | US8575145, 92 | US8575145, 92/122)
Affinity DataIC50:  1nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase pim-3(Rattus norvegicus (Rat))
Array Biopharma

US Patent
LigandPNGBDBM104215(US8575145, 152 | US8575145, 92 | US8575145, 92/122)
Affinity DataIC50:  23.5nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM104215(US8575145, 152 | US8575145, 92 | US8575145, 92/122)
Affinity DataIC50:  1.00E+3nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase pim-3(Rattus norvegicus (Rat))
Array Biopharma

US Patent
LigandPNGBDBM104215(US8575145, 152 | US8575145, 92 | US8575145, 92/122)
Affinity DataIC50:  3nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM104215(US8575145, 152 | US8575145, 92 | US8575145, 92/122)
Affinity DataIC50:  244nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
In DepthDetails US Patent