BDBM10592 7-chloro-15-methyl-10-azatetracyclo[11.3.1.0^{2,11}.0^{4,9}]heptadeca-2,4(9),5,7,10,14-hexaen-3-amine::CHEMBL140476::Huprine Y.HCl::US9238626, (+/-)-Huprine Y HCl
SMILES CC1=CC2CC(C1)c1c(C2)nc2cc(Cl)ccc2c1N
InChI Key InChIKey=UKCBMHDZLYYTMI-UHFFFAOYSA-N
Data 43 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 13 hits for monomerid = 10592
Affinity DataIC50: 181nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as a substrate preincubated for 20 mins followed by substrate addition by spectrophoto...More data for this Ligand-Target Pair
Affinity DataIC50: 181nMpH: 8.0 T: 2°CAssay Description:BChE inhibitory activity determinations were carried out similarly by
the method of Ellman et al., using 0.02 unit/mL of human serum BChE and
300 u...More data for this Ligand-Target Pair
Affinity DataIC50: 181nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 175nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide preincubated for 20 mins before substrate addition by Ellman methodMore data for this Ligand-Target Pair
Affinity DataIC50: 247nMAssay Description:Inhibition of butyrylcholinesterase (BChE) in human serumMore data for this Ligand-Target Pair
Affinity DataIC50: 247nMAssay Description:Inhibition of butyrylcholinesterase (BChE) in human serumMore data for this Ligand-Target Pair
Affinity DataIC50: 236nMAssay Description:Inhibition of butyrylcholinesterase (BChE) in human serumMore data for this Ligand-Target Pair
Affinity DataIC50: 247nMAssay Description:Inhibition of human serum butyrylcholinesterase using butyrylthiocholine iodide as substrate incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 236nMAssay Description:Inhibition of human serum butyrylcholinesterase using butyrylthiocholine iodide as substrate incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 236nMAssay Description:Inhibition of human serum butyrylcholinesterase using butyrylthiocholine iodide as substrate incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 181nMAssay Description:Inhibition of human serum BChE using butyrylthiocholineiodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 358nMAssay Description:Inhibition of recombinant human BuChE using butyrylthiocholine as substrate by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 236nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair