BDBM10614 (3aS)-3a,8-dimethyl-2H,3H,3aH,8H,8aH-furo[2,3-b]indol-5-yl N-methylcarbamate::CHEMBL362444::Physovenine Carbamate 20a

SMILES CNC(=O)Oc1ccc2N(C)C3OCC[C@@]3(C)c2c1

InChI Key InChIKey=LXTKNVLLWOLCOV-PYMCNQPYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 10614   

TargetAcetylcholinesterase(Homo sapiens (Human))
National Institutes of Health

LigandPNGBDBM10614((3aS)-3a,8-dimethyl-2H,3H,3aH,8H,8aH-furo[2,3-b]in...)
Affinity DataIC50:  27nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
National Institutes of Health

LigandPNGBDBM10614((3aS)-3a,8-dimethyl-2H,3H,3aH,8H,8aH-furo[2,3-b]in...)
Affinity DataIC50:  4nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
National Institutes of Health

LigandPNGBDBM10614((3aS)-3a,8-dimethyl-2H,3H,3aH,8H,8aH-furo[2,3-b]in...)
Affinity DataIC50:  27nMAssay Description:Inhibitory concentration against human erythrocyte AcetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
National Institutes of Health

LigandPNGBDBM10614((3aS)-3a,8-dimethyl-2H,3H,3aH,8H,8aH-furo[2,3-b]in...)
Affinity DataIC50:  4nMAssay Description:Inhibition of BuchE (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
National Institutes of Health

LigandPNGBDBM10614((3aS)-3a,8-dimethyl-2H,3H,3aH,8H,8aH-furo[2,3-b]in...)
Affinity DataIC50:  4nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
National Institutes of Health

LigandPNGBDBM10614((3aS)-3a,8-dimethyl-2H,3H,3aH,8H,8aH-furo[2,3-b]in...)
Affinity DataIC50:  4nMAssay Description:Inhibition of BuChE (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
National Institutes of Health

LigandPNGBDBM10614((3aS)-3a,8-dimethyl-2H,3H,3aH,8H,8aH-furo[2,3-b]in...)
Affinity DataIC50:  27nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCholinesterase(Homo sapiens (Human))
National Institutes of Health

LigandPNGBDBM10614((3aS)-3a,8-dimethyl-2H,3H,3aH,8H,8aH-furo[2,3-b]in...)
Affinity DataIC50:  4nMAssay Description:Inhibitory concentration against human plasma ButyrylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed