BDBM10619 (4-Isopropyl-phenyl)-carbamic acid (S)-3a,8-dimethyl-3,3a,8,8a-tetrahydro-2H-furo[2,3-b]indol-5-yl ester::CHEMBL178132::Physovenine Carbamate 23a

SMILES CC(C)c1ccc(NC(=O)Oc2ccc3N(C)C4OCC[C@@]4(C)c3c2)cc1

InChI Key InChIKey=NPANUSRHFVUOKM-IAXKEJLGSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 10619   

TargetAcetylcholinesterase(Homo sapiens (Human))
National Institutes of Health

LigandPNGBDBM10619((4-Isopropyl-phenyl)-carbamic acid (S)-3a,8-dimeth...)
Affinity DataIC50:  3.86E+3nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
National Institutes of Health

LigandPNGBDBM10619((4-Isopropyl-phenyl)-carbamic acid (S)-3a,8-dimeth...)
Affinity DataIC50:  3.86E+3nMAssay Description:Inhibitory concentration against human erythrocyte AcetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM10619((4-Isopropyl-phenyl)-carbamic acid (S)-3a,8-dimeth...)
Affinity DataIC50:  17nMAssay Description:Inhibitory concentration against human plasma ButyrylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM10619((4-Isopropyl-phenyl)-carbamic acid (S)-3a,8-dimeth...)
Affinity DataIC50:  17nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed