BDBM106369 ZYJ-34v (Compound 2)

SMILES CCCC(CCC)C(=O)N1Cc2cc(OCC(=O)NO)ccc2C[C@H]1C(=O)Nc1ccc(OC)cc1

InChI Key InChIKey=UAAORBBFESJLFV-DEOSSOPVSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 106369   

TargetHistone deacetylase 1(Homo sapiens (Human))
Shandong University

LigandPNGBDBM106369(ZYJ-34v (Compound 2))
Affinity DataIC50:  37.6nMT: 2°CAssay Description:Bos-Lys (acetyl)-4-amino-7-methylcoumarin substrate was used in inhibition assays against class I (HDAC1, HDAC2, HDAC3) and class IIb (HDAC6), while ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Shandong University

LigandPNGBDBM106369(ZYJ-34v (Compound 2))
Affinity DataIC50:  675nMT: 2°CAssay Description:Bos-Lys (acetyl)-4-amino-7-methylcoumarin substrate was used in inhibition assays against class I (HDAC1, HDAC2, HDAC3) and class IIb (HDAC6), while ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Shandong University

LigandPNGBDBM106369(ZYJ-34v (Compound 2))
Affinity DataIC50:  87.7nMT: 2°CAssay Description:Bos-Lys (acetyl)-4-amino-7-methylcoumarin substrate was used in inhibition assays against class I (HDAC1, HDAC2, HDAC3) and class IIb (HDAC6), while ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Shandong University

LigandPNGBDBM106369(ZYJ-34v (Compound 2))
Affinity DataIC50:  175nMT: 2°CAssay Description:Bos-Lys (acetyl)-4-amino-7-methylcoumarin substrate was used in inhibition assays against class I (HDAC1, HDAC2, HDAC3) and class IIb (HDAC6), while ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed