BDBM106608 CHEMBL2206388::US8586617, 113

SMILES COc1cccc(n1)N(Cc1cnc[nH]1)C(C)C

InChI Key InChIKey=HXJNMJJXCIYGOW-UHFFFAOYSA-N

Data  2 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 106608   

TargetTrace amine-associated receptor 1(Mus musculus (Mouse))
Hoffmann-La Roche

US Patent
LigandPNGBDBM106608(CHEMBL2206388 | US8586617, 113)
Affinity DataKi:  2.40nM ΔG°:  -10.9kcal/moleT: 2°CAssay Description:Radioligand binding assay: The radioligand [3H]-rac-2-(1,2,3,4-tetrahydro-1-naphthyl)-2-imidazoline was used at a concentration equal to the calcula...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTrace amine-associated receptor 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM106608(CHEMBL2206388 | US8586617, 113)
Affinity DataKi:  12nMAssay Description:Displacement of (S)-4-(2,4-difluorophenyl-3-tritio) -4,5-dihydro-2-oxazolamine from human TAAR1 receptor expressed in HEK293 cells after 90 mins by b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrace amine-associated receptor 1(Mus musculus (Mouse))
Hoffmann-La Roche

US Patent
LigandPNGBDBM106608(CHEMBL2206388 | US8586617, 113)
Affinity DataEC50:  98nMAssay Description:Agonist activity at mouse TAAR1 receptor expressed in HEK293 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrace amine-associated receptor 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM106608(CHEMBL2206388 | US8586617, 113)
Affinity DataEC50:  40nMAssay Description:Agonist activity at human TAAR1 receptor expressed in HEK293 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrace amine-associated receptor 1(Rattus norvegicus (Rat))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM106608(CHEMBL2206388 | US8586617, 113)
Affinity DataEC50:  25nMAssay Description:Agonist activity at rat TAAR1 receptor expressed in HEK293 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed