BDBM10866 4-amino-6-(trifluoromethyl)benzene-1,3-disulfonamide::CHEMBL418::aromatic/heteroaromatic sulfonamide 11

SMILES Nc1cc(c(cc1S(N)(=O)=O)S(N)(=O)=O)C(F)(F)F

InChI Key InChIKey=KRVABEGPNKGLOT-UHFFFAOYSA-N

Data  102 KI  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 10866   

TargetCarbonic anhydrase 2(Homo sapiens (Human))
Recep Tayyip Erdogan University

Curated by ChEMBL
LigandPNGBDBM10866(4-amino-6-(trifluoromethyl)benzene-1,3-disulfonami...)
Affinity DataKi:  63nMAssay Description:Inhibition of human carbonic anhydrase 2 incubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Recep Tayyip Erdogan University

Curated by ChEMBL
LigandPNGBDBM10866(4-amino-6-(trifluoromethyl)benzene-1,3-disulfonami...)
Affinity DataKi:  5.80E+3nMAssay Description:Inhibition of human carbonic anhydrase 1 incubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed