BDBM10951 (2S,6R)-3-methyl-8-oxa-3-azatricyclo[7.4.0.0^{2,6}]trideca-1(13),9,11-trien-10-yl N-methylcarbamate::Conformationally Restricted Rivastigmine Analogue 3
SMILES [H][C@@]12CCN(C)[C@]1([H])c1cccc(OC(=O)NC)c1OC2
InChI Key InChIKey=UKFCIGJAJAIROZ-CABZTGNLSA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 10951
Affinity DataIC50: 30nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
Affinity DataIC50: 59.4nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
Affinity DataIC50: 74.1nMAssay Description:Inhibitory activity against acetylcholinesterase in human erythrocytesMore data for this Ligand-Target Pair
Affinity DataIC50: 74.1nMAssay Description:Inhibitory activity against acetylcholinesterase in human erythrocytesMore data for this Ligand-Target Pair
Affinity DataIC50: 74.1nMAssay Description:Inhibitory activity against acetylcholinesterase in human erythrocytesMore data for this Ligand-Target Pair
Affinity DataIC50: 54nMAssay Description:Inhibitory activity against butyrylcholinesterase (BChE) in human erythrocyteMore data for this Ligand-Target Pair
Affinity DataIC50: 54nMAssay Description:Inhibitory activity against butyrylcholinesterase (BChE) in human erythrocyteMore data for this Ligand-Target Pair
Affinity DataIC50: 54nMAssay Description:Inhibitory activity against butyrylcholinesterase (BChE) in human erythrocyteMore data for this Ligand-Target Pair