BDBM109773 US8609708, 74 Anabaseine

SMILES C1CCC(=NC1)c1cccnc1

InChI Key InChIKey=AUBPMADJYNSPOA-UHFFFAOYSA-N

Data  5 KI  1 IC50  2 EC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 109773   

TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM109773(US8609708, 74 Anabaseine)
Affinity DataKi:  32nMAssay Description:Binding affinity to rat alpha4beta2 nAChRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM109773(US8609708, 74 Anabaseine)
Affinity DataKi:  32nMAssay Description:Displacement of [125I] alpha bungarotoxin from rat alpha7 nACh receptor expressed in rat hippocampal membrane preincubated for 30 mins followed by ra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM109773(US8609708, 74 Anabaseine)
Affinity DataKi:  58nMAssay Description:Binding affinity to rat alpha7 nAChRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM109773(US8609708, 74 Anabaseine)
Affinity DataKi:  67nMAssay Description:Displacement of [3H]-epibatidine from rat alpha4beta2 nACh receptor expressed in rat cortical membrane preincubated for 30 mins followed by radioliga...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM109773(US8609708, 74 Anabaseine)
Affinity DataKi:  107nMAssay Description:Displacement of [3H]-epibatidine from human alpha3beta4 nACh receptor expressed in HEK293 cells preincubated for 5 mins followed by radioligand addit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM109773(US8609708, 74 Anabaseine)
Affinity DataEC50:  4.20E+3nMAssay Description:Agonist activity at rat alpha4beta2 nAChRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM109773(US8609708, 74 Anabaseine)
Affinity DataEC50:  6.70E+3nMAssay Description:Agonist activity at rat alpha7 nAChRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2A6(Homo sapiens (Human))
Human Biomolecular Research Institute

US Patent
LigandPNGBDBM109773(US8609708, 74 Anabaseine)
Affinity DataIC50:  1.20E+5nMAssay Description:The inhibition of human CYP2A6-mediated 7-hydroxy coumarin formation was evaluated in the presence of 95 selected test compounds in a standard assay ...More data for this Ligand-Target Pair
In DepthDetails US Patent