BDBM110037 US8609678, 2-((2,6-dimethylphenyl)(phenyl)amino)-N-(7-(hydroxyamino)-7-oxoheptyl)pyrimidine-5-carboxamide [90]

SMILES Cc1cccc(C)c1N(c1ccccc1)c1ncc(cn1)C(=O)NCCCCCCC(=O)NO

InChI Key InChIKey=JRKWOWIYKUDTNB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 110037   

TargetHistone deacetylase 6(Homo sapiens (Human))
Acetylon Pharmaceuticals

US Patent
LigandPNGBDBM110037(US8609678, 2-((2,6-dimethylphenyl)(phenyl)amino)-N...)
Affinity DataIC50:  137nMpH: 7.4Assay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
Acetylon Pharmaceuticals

US Patent
LigandPNGBDBM110037(US8609678, 2-((2,6-dimethylphenyl)(phenyl)amino)-N...)
Affinity DataIC50:  5nMpH: 7.4Assay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
In DepthDetails US Patent