BDBM111820 (2E,5E)‐2,5‐bis(2‐phenylpropylidene)cyclopentan‐1‐ one (16)

SMILES CC(C=C1CCC(=CC(C)c2ccccc2)C1=O)c1ccccc1

InChI Key InChIKey=VNJURRGINSXXRH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 111820   

TargetProstaglandin E synthase(Homo sapiens (Human))
Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, 50300, Kuala Lumpur, Malaysia

LigandPNGBDBM111820((2E,5E)‐2,5‐bis(2‐phenylpropylid...)
Affinity DataIC50:  7.48E+3nMpH: 7.0 T: 2°CAssay Description:The assay buffer contained 100 mM KHPO4 (pH 7.0), 2 mM EDTA and 2.5 mM reduced GSH. 100 µL of reaction buffer containing human recombinant mPGES...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, 50300, Kuala Lumpur, Malaysia

LigandPNGBDBM111820((2E,5E)‐2,5‐bis(2‐phenylpropylid...)
Affinity DataIC50:  3.20E+5nMpH: 8.0 T: 2°CAssay Description:Reaction mixture containing 100 mM Tris-HCl buffer (pH 8) and COX-1 (ovine) or COX-2 (human recombinant) was preincubated for 10 min in a water bath ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed