BDBM113588 US8633196, 18::US9365529, 18

SMILES Cc1cc(COc2ccc(cc2)S(=O)(=O)NC[C@H](N2CCN(Cc3ccc(F)cc3)CC2)C(=O)NO)c2ccccc2n1

InChI Key InChIKey=UWCNFKCKFSEPKW-PMERELPUSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 113588   

TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM113588(US8633196, 18 | US9365529, 18)
Affinity DataIC50:  67nMpH: 7.4 T: 2°CAssay Description:The TACE enzyme is an internal production (carried out according to the publication protein Eng Des Sel 2006, 19, 155-161) and is added so as to have...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM113588(US8633196, 18 | US9365529, 18)
Affinity DataIC50:  67nMpH: 7.4 T: 2°CAssay Description:The TACE enzyme is an internal production (carried out according to the publication protein Eng Des Sel 2006, 19, 155-161) and is added so as to have...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetInterstitial collagenase(Homo sapiens (Human))
Galderma Research & Devlopment

US Patent
LigandPNGBDBM113588(US8633196, 18 | US9365529, 18)
Affinity DataIC50:  670nMAssay Description:The molecules are dose-response tested on the following enzymes: MMP1, MMP3, MMP9, ADAM9 and ADAM10, according to the same protocol as that described...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDisintegrin and metalloproteinase domain-containing protein 9(Homo sapiens (Human))
Galderma Research & Devlopment

US Patent
LigandPNGBDBM113588(US8633196, 18 | US9365529, 18)
Affinity DataIC50:  9.25E+3nMAssay Description:The molecules are dose-response tested on the following enzymes: MMP1, MMP3, MMP9, ADAM9 and ADAM10, according to the same protocol as that described...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Galderma Research & Devlopment

US Patent
LigandPNGBDBM113588(US8633196, 18 | US9365529, 18)
Affinity DataIC50: >1.00E+4nMAssay Description:The molecules are dose-response tested on the following enzymes: MMP1, MMP3, MMP9, ADAM9 and ADAM10, according to the same protocol as that described...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDisintegrin and metalloproteinase domain-containing protein 10(Homo sapiens (Human))
Galderma Research & Devlopment

US Patent
LigandPNGBDBM113588(US8633196, 18 | US9365529, 18)
Affinity DataIC50: >1.00E+4nMAssay Description:The molecules are dose-response tested on the following enzymes: MMP1, MMP3, MMP9, ADAM9 and ADAM10, according to the same protocol as that described...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetStromelysin-1(Homo sapiens (Human))
Galderma Research & Devlopment

US Patent
LigandPNGBDBM113588(US8633196, 18 | US9365529, 18)
Affinity DataIC50:  849nMAssay Description:The molecules are dose-response tested on the following enzymes: MMP1, MMP3, MMP9, ADAM9 and ADAM10, according to the same protocol as that described...More data for this Ligand-Target Pair
In DepthDetails US Patent