BDBM115367 US8637500, 188
SMILES N(c1ccc(Oc2nccnc2-c2ccncc2)cc1)c1ccccn1
InChI Key InChIKey=RFGOJFDMXXDVHC-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 115367
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rattus norvegicus (rat))
Amgen
US Patent
Amgen
US Patent
Affinity DataIC50: 5nMT: 2°CAssay Description:An IMAP TR-FRET assay was used to analyze the enzyme activity (Molecular Devices Corp., Sunnyvale Calif.). 5 μL of serial diluted PDE10A (BPS Bi...More data for this Ligand-Target Pair