BDBM11557 (2S)-1-[(3R)-3-amino-4-phenylbutanoyl]-N-({5-chloro-2-[(cyclopropylcarbamoyl)methoxy]phenyl}methyl)pyrrolidine-2-carboxamide::CHEMBL184738::proline derivative 7

SMILES N[C@@H](CC(=O)N1CCC[C@H]1C(=O)NCc1cc(Cl)ccc1OCC(=O)NC1CC1)Cc1ccccc1

InChI Key InChIKey=FEFCYNYYEURJOF-GGAORHGYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 11557   

TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM11557((2S)-1-[(3R)-3-amino-4-phenylbutanoyl]-N-({5-chlor...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibitory concentration against Dipeptidyl peptidase IVMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM11557((2S)-1-[(3R)-3-amino-4-phenylbutanoyl]-N-({5-chlor...)
Affinity DataIC50:  1.90E+3nMpH: 7.4 T: 2°CAssay Description:The DPP4 activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 370 nm and mea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed