BDBM11654 (2S,3S)-2-amino-1-(pyrrolidin-1-yl)-3-{3-[4-(trifluoromethoxy)phenyl]-1,2,4-oxadiazol-5-yl}butan-1-one::CHEMBL220249::alpha-amino acid pyrrolidide 16::oxadiazole based amide

SMILES C[C@@H]([C@H](N)C(=O)N1CCCC1)c1nc(no1)-c1ccc(OC(F)(F)F)cc1

InChI Key InChIKey=DAWNZHPPZUPTMH-GWCFXTLKSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 11654   

TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM11654((2S,3S)-2-amino-1-(pyrrolidin-1-yl)-3-{3-[4-(trifl...)
Affinity DataIC50:  1.79E+3nMpH: 7.5 T: 2°CAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM11654((2S,3S)-2-amino-1-(pyrrolidin-1-yl)-3-{3-[4-(trifl...)
Affinity DataIC50:  5.20E+3nMAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM11654((2S,3S)-2-amino-1-(pyrrolidin-1-yl)-3-{3-[4-(trifl...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of DPP8 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 9(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM11654((2S,3S)-2-amino-1-(pyrrolidin-1-yl)-3-{3-[4-(trifl...)
Affinity DataIC50: >1.00E+5nMAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM11654((2S,3S)-2-amino-1-(pyrrolidin-1-yl)-3-{3-[4-(trifl...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of DPP4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM11654((2S,3S)-2-amino-1-(pyrrolidin-1-yl)-3-{3-[4-(trifl...)
Affinity DataIC50: >1.00E+5nMAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed