BDBM11987 2-hydroxy-5-(5-{[(5Z)-2-imino-4-oxo-3-(1,3-thiazol-2-yl)-1,3-thiazolidin-5-ylidene]methyl}furan-2-yl)benzoic acid::chemical diversity library compound 12

SMILES OC(=O)c1cc(ccc1O)-c1ccc(\C=C2/SC(=N)N(C2=O)c2nccs2)o1

InChI Key InChIKey=RJZWEPFYPQHKQE-PUOZGBORSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 11987   

TargetLethal factor(Bacillus anthracis)
Montana State University

LigandPNGBDBM11987(2-hydroxy-5-(5-{[(5Z)-2-imino-4-oxo-3-(1,3-thiazol...)
Affinity DataKi:  3.10E+3nM ΔG°:  -7.56kcal/mole IC50:  4.20E+3nMpH: 7.2 T: 2°CAssay Description:For selected lead compounds from fluorescence-based high-throughput screening, Km and Vmax were calculated using the double-reciprocal Lineweaver-Bur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed