BDBM11990 4-(5-{[(3E)-5-cyano-2-hydroxy-4-methyl-6-oxo-3,6-dihydropyridin-3-ylidene]methyl}furan-2-yl)benzene-1-sulfonamide::chemical diversity library compound 15

SMILES NS(=O)(=O)c1ccc(cc1)-c1ccc(C=c2c(=O)[nH]c(O)c(C#N)c2=C)o1

InChI Key InChIKey=ARTWDZADTHIUKE-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 11990   

TargetLethal factor(Bacillus anthracis)
Montana State University

LigandPNGBDBM11990(4-(5-{[(3E)-5-cyano-2-hydroxy-4-methyl-6-oxo-3,6-d...)
Affinity DataKi:  5.40E+3nM ΔG°:  -7.23kcal/mole IC50:  1.08E+4nMpH: 7.2 T: 2°CAssay Description:For selected lead compounds from fluorescence-based high-throughput screening, Km and Vmax were calculated using the double-reciprocal Lineweaver-Bur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed