BDBM120133 US8697708, 22

SMILES Cc1cc(Nc2nccc3nc(sc23)-c2c(Cl)cc(CO)cc2Cl)ncn1

InChI Key InChIKey=MAFZJJYDINWFCS-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 120133   

TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM120133(US8697708, 22)
Affinity DataKi:  1nM ΔG°:  -12.1kcal/molepH: 7.2 T: 2°CAssay Description:To determine the inhibition constants (Ki) of Examples 1-240, compounds were diluted serially in DMSO and added to 50 μL kinase reactions contai...More data for this Ligand-Target Pair
In DepthDetails US Patent