BDBM12047 (3S)-3-benzenesulfonamido-4-oxobutanoic acid::(S)-3-Benzenesulfonylamino-4-oxo-butyric acid::arylsulfonamide analogue 11

SMILES OC(=O)C[C@H](NS(=O)(=O)c1ccccc1)C=O

InChI Key InChIKey=QYUCWQDDSAPZAF-QMMMGPOBSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 12047   

TargetCaspase-1(Homo sapiens (Human))
Pfizer

LigandPNGBDBM12047((3S)-3-benzenesulfonamido-4-oxobutanoic acid | (S)...)
Affinity DataKi:  9.40E+3nM ΔG°:  -7.13kcal/molepH: 7.0 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed