BDBM12054 (3S)-3-{[2-(3-acetamidophenyl)benzene]sulfonamido}-4-oxobutanoic acid::(S)-3-(3-Acetylamino-biphenyl-2-sulfonylamino)-4-oxo-butyric acid::arylsulfonamide analogue 18

SMILES CC(=O)Nc1cccc(c1)-c1ccccc1S(=O)(=O)N[C@@H](CC(O)=O)C=O

InChI Key InChIKey=GKCMBVXIDHHNSD-HNNXBMFYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 12054   

TargetCaspase-1(Homo sapiens (Human))
Pfizer

LigandPNGBDBM12054((3S)-3-{[2-(3-acetamidophenyl)benzene]sulfonamido}...)
Affinity DataKi:  2.30E+3nM ΔG°:  -8.00kcal/molepH: 7.0 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed