BDBM12057 (3S)-3-{[2-(2-methylphenoxy)benzene]sulfonamido}-4-oxobutanoic acid::Diphenyl Ether Sulfonamide 3

SMILES Cc1ccccc1Oc1ccccc1S(=O)(=O)N[C@@H](CC(O)=O)C=O

InChI Key InChIKey=NIWORFZHCLVJEB-ZDUSSCGKSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 12057   

TargetCaspase-1(Homo sapiens (Human))
Pfizer

LigandPNGBDBM12057((3S)-3-{[2-(2-methylphenoxy)benzene]sulfonamido}-4...)
Affinity DataKi:  3.00E+3nM ΔG°:  -7.83kcal/molepH: 7.0 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed