BDBM12060 (3S)-3-{[2-(2,3-dimethylphenoxy)benzene]sulfonamido}-4-oxobutanoic acid::Diphenyl Ether Sulfonamide 6

SMILES Cc1cccc(Oc2ccccc2S(=O)(=O)N[C@@H](CC(O)=O)C=O)c1C

InChI Key InChIKey=FYRXOMRJOXACFZ-AWEZNQCLSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 12060   

TargetCaspase-1(Homo sapiens (Human))
Pfizer

LigandPNGBDBM12060((3S)-3-{[2-(2,3-dimethylphenoxy)benzene]sulfonamid...)
Affinity DataKi:  1.00E+3nM ΔG°:  -8.51kcal/molepH: 7.0 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed