BDBM12063 (3S)-4-oxo-3-({2-[4-(propan-2-yl)phenoxy]benzene}sulfonamido)butanoic acid::Diphenyl Ether Sulfonamide 9

SMILES CC(C)c1ccc(Oc2ccccc2S(=O)(=O)N[C@@H](CC(O)=O)C=O)cc1

InChI Key InChIKey=AEPYMMPLKGNMAN-HNNXBMFYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 12063   

TargetCaspase-1(Homo sapiens (Human))
Pfizer

LigandPNGBDBM12063((3S)-4-oxo-3-({2-[4-(propan-2-yl)phenoxy]benzene}s...)
Affinity DataKi:  620nM ΔG°:  -8.80kcal/molepH: 7.0 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed