BDBM12069 (3S)-3-{[2-(4-cyclohexylphenoxy)benzene]sulfonamido}-4-oxobutanoic acid::Diphenyl Ether Sulfonamide 15

SMILES OC(=O)C[C@H](NS(=O)(=O)c1ccccc1Oc1ccc(cc1)C1CCCCC1)C=O

InChI Key InChIKey=IFSXVBUWEGXUIU-SFHVURJKSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 12069   

TargetCaspase-1(Homo sapiens (Human))
Pfizer

LigandPNGBDBM12069((3S)-3-{[2-(4-cyclohexylphenoxy)benzene]sulfonamid...)
Affinity DataKi:  900nM ΔG°:  -8.57kcal/molepH: 7.0 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed