BDBM12070 (3S)-4-oxo-3-{[2-(4-phenylphenoxy)benzene]sulfonamido}butanoic acid::Diphenyl Ether Sulfonamide 16

SMILES OC(=O)C[C@H](NS(=O)(=O)c1ccccc1Oc1ccc(cc1)-c1ccccc1)C=O

InChI Key InChIKey=LGXCMURWCNVCSW-SFHVURJKSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 12070   

TargetCaspase-1(Homo sapiens (Human))
Pfizer

LigandPNGBDBM12070((3S)-4-oxo-3-{[2-(4-phenylphenoxy)benzene]sulfonam...)
Affinity DataKi:  290nM ΔG°:  -9.27kcal/molepH: 7.0 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed