BDBM12082 ((2-chloro-5-methyl-phenyl)-{6-[4-(3-(dimethylamino)-2-hydroxy-propoxy)-phenylamino]-pyrimidin-4-yl}-amino)-acetonitrile::2-[(2-chloro-5-methylphenyl)[6-({4-[(2R)-3-(dimethylamino)-2-hydroxypropoxy]phenyl}amino)pyrimidin-4-yl]amino]acetonitrile::AZ2
SMILES CN(C)C[C@@H](O)COc1ccc(Nc2cc(ncn2)N(CC#N)c2cc(C)ccc2Cl)cc1
InChI Key InChIKey=FIRZNFNHYVXQPP-LJQANCHMSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 12082
Affinity DataIC50: 2.60E+3nMpH: 7.5 T: 30°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 12.5 uM ATP/ [ga...More data for this Ligand-Target Pair
Affinity DataIC50: 140nMpH: 7.5 T: 30°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 12.5 uM ATP/ [ga...More data for this Ligand-Target Pair
Affinity DataIC50: 47nMpH: 7.5 T: 30°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 12.5 uM ATP/ [ga...More data for this Ligand-Target Pair
TargetCyclin-A2 [171-432]/Cyclin-dependent kinase 2 [F82H,L83V,H84D,K98T](Human)
University of Oxford
University of Oxford
Affinity DataIC50: 640nMpH: 7.5 T: 30°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 12.5 uM ATP/ [ga...More data for this Ligand-Target Pair
Affinity DataIC50: 7.30E+3nMpH: 7.5 T: 30°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 12.5 uM ATP/ [ga...More data for this Ligand-Target Pair