BDBM120950 US8716285, 7

SMILES ONC(=O)c1ccc2CCC(Cc2c1)Nc1ncccn1

InChI Key InChIKey=JPOSGBAFUMSWBQ-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 120950   

TargetHistone deacetylase 6(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development

Curated by ChEMBL
LigandPNGBDBM120950(US8716285, 7)
Affinity DataEC50:  730nMAssay Description:Inhibition of HDAC6 in human A549 cells assessed as tubulin acetylation after 17 to 18 hrs by cytoblot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM120950(US8716285, 7)
Affinity DataIC50:  730nMAssay Description:Compounds were tested for their ability to inhibit histone deacetylase 8 using an in vitro deacetylation assay. In a detailed procedure, 8 μl o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent