BDBM121145 US8722896, (+/-)-2-Methyl-3-((2- methoxybenzyl)methylamino)- N-(9-chloro-3,4-dihydro-2H-1,5- benzodioxepin-7-ylmethyl)-N- isobutylpropanamide

SMILES COc1cccc(CNCC(C)C(=O)N(CC(C)C)Cc2cc(Cl)c3OCCCOc3c2)c1

InChI Key InChIKey=MXIJKVHYCHHNIH-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 121145   

TargetProkineticin receptor 2(Cricetulus griseus (Chinese hamster))
The Regents of The University of California

US Patent
LigandPNGBDBM121145(US8722896, (+/-)-2-Methyl-3-((2- methoxybenzyl)met...)
Affinity DataKi:  1.76nM ΔG°:  -12.4kcal/moleT: 2°CAssay Description:An aequorin-based luminescent assay for calcium mobilization was used to measure mobilization of intracellular Ca2+ (Bullock et al., Mol Pharmacol 65...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProkineticin receptor 1(Cricetulus griseus (Chinese hamster))
The Regents of The University of California

US Patent
LigandPNGBDBM121145(US8722896, (+/-)-2-Methyl-3-((2- methoxybenzyl)met...)
Affinity DataKi:  7.26nM ΔG°:  -11.5kcal/moleT: 2°CAssay Description:An aequorin-based luminescent assay for calcium mobilization was used to measure mobilization of intracellular Ca2+ (Bullock et al., Mol Pharmacol 65...More data for this Ligand-Target Pair
In DepthDetails US Patent