BDBM121290 US8722896, (+/-)-(3R)-4-(Indol-7-ylmethyl)- N-(9-chloro-2,3,4,5-tetrahydro- 1-benzoxepin-7-ylmethyl)-N- isobutylpiperidine-2- carboxamide

SMILES CC(C)CN(Cc1cc(Cl)c2OCCCCc2c1)C(=O)C1CN(Cc2cccc3cc[nH]c23)CCO1

InChI Key InChIKey=MNZUQWHEVHRCQC-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 121290   

TargetProkineticin receptor 2(Cricetulus griseus (Chinese hamster))
The Regents of The University of California

US Patent
LigandPNGBDBM121290(US8722896, (+/-)-(3R)-4-(Indol-7-ylmethyl)- N-(9-c...)
Affinity DataKi:  1.94nM ΔG°:  -12.4kcal/moleT: 2°CAssay Description:An aequorin-based luminescent assay for calcium mobilization was used to measure mobilization of intracellular Ca2+ (Bullock et al., Mol Pharmacol 65...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProkineticin receptor 1(Cricetulus griseus (Chinese hamster))
The Regents of The University of California

US Patent
LigandPNGBDBM121290(US8722896, (+/-)-(3R)-4-(Indol-7-ylmethyl)- N-(9-c...)
Affinity DataKi:  4.02nM ΔG°:  -11.9kcal/moleT: 2°CAssay Description:An aequorin-based luminescent assay for calcium mobilization was used to measure mobilization of intracellular Ca2+ (Bullock et al., Mol Pharmacol 65...More data for this Ligand-Target Pair
In DepthDetails US Patent