BDBM121300 US8722896, (-)-(3R)-1-(N-methyl-indol-4- ylmethyl)-N-(9-chloro-2,3,4,5- tetrahydro-1-benzoxepin-7- ylmethyl)-N-isobutylpiperidine- 3-carboxamide

SMILES CC(C)CN(Cc1cc(Cl)c2OCCCCc2c1)C(=O)C1CCCN(Cc2cccc3n(C)ccc23)C1

InChI Key InChIKey=TUPQMRFXFANGOP-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 121300   

TargetProkineticin receptor 1(Cricetulus griseus (Chinese hamster))
The Regents of The University of California

US Patent
LigandPNGBDBM121300(US8722896, (-)-(3R)-1-(N-methyl-indol-4- ylmethyl)...)
Affinity DataKi:  4.72nM ΔG°:  -11.8kcal/moleT: 2°CAssay Description:An aequorin-based luminescent assay for calcium mobilization was used to measure mobilization of intracellular Ca2+ (Bullock et al., Mol Pharmacol 65...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProkineticin receptor 2(Cricetulus griseus (Chinese hamster))
The Regents of The University of California

US Patent
LigandPNGBDBM121300(US8722896, (-)-(3R)-1-(N-methyl-indol-4- ylmethyl)...)
Affinity DataKi:  303nM ΔG°:  -9.24kcal/moleT: 2°CAssay Description:An aequorin-based luminescent assay for calcium mobilization was used to measure mobilization of intracellular Ca2+ (Bullock et al., Mol Pharmacol 65...More data for this Ligand-Target Pair
In DepthDetails US Patent