BDBM12185 2-[(2S)-2-amino-2-cyclohexylacetyl]-1,2,3,4-tetrahydroisoquinoline-1-carbonitrile::isoquinoline derivative 8

SMILES N[C@@H](C1CCCCC1)C(=O)N1CCc2ccccc2C1C#N

InChI Key InChIKey=KGDBQBLVFYQEHN-DJNXLDHESA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 12185   

TargetDipeptidyl peptidase 8(Homo sapiens (Human))
National Health Research Institutes

LigandPNGBDBM12185(2-[(2S)-2-amino-2-cyclohexylacetyl]-1,2,3,4-tetrah...)
Affinity DataIC50:  5.96E+3nMpH: 8.0 T: 2°CAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
National Health Research Institutes

LigandPNGBDBM12185(2-[(2S)-2-amino-2-cyclohexylacetyl]-1,2,3,4-tetrah...)
Affinity DataIC50: >1.00E+5nMAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
National Health Research Institutes

LigandPNGBDBM12185(2-[(2S)-2-amino-2-cyclohexylacetyl]-1,2,3,4-tetrah...)
Affinity DataIC50: >1.00E+5nMAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed