BDBM123099 US10723709, Example 3::US11312693, Example 3::US8735395, 3
SMILES CC(C)C[C@H](NC(=O)c1ccc(-c2csc(n2)N2CCN(C)CC2)c(F)c1)C(=O)N1C[C@@H](C#C)[C@H]2OCC(=O)[C@@H]12
InChI Key InChIKey=RFCUHPQJTGIXFS-GTKJVGNCSA-N
Data 14 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 14 hits for monomerid = 123099
Affinity DataKi: 4nMpH: 7.0Assay Description:Standard assay conditions for the determination of kinetic constants used a fluorogenic peptide substrate, typically H-D-Ala-Leu-Lys-AMC, and were de...More data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:The recombinant cathepsin K can be expressed in a variety of commercially available expression systems including E coli, Pichia and Baculovirus syste...More data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Standard assay conditions for the determination of kinetic constants used a fluorogenic peptide substrate, typically H-D-Ala-Leu-Lys-AMC, and were de...More data for this Ligand-Target Pair
Affinity DataKi: <50nMAssay Description:Standard assay conditions for the determination of kinetic constants used a fluorogenic peptide substrate, typically H-D-Ala-Leu-Lys-AMC, and were de...More data for this Ligand-Target Pair
Affinity DataKi: <50nMAssay Description:The recombinant cathepsin K can be expressed in a variety of commercially available expression systems including E coli, Pichia and Baculovirus syste...More data for this Ligand-Target Pair
Affinity DataKi: 750nMAssay Description:The enzyme is commercially available human cathepsin L. The substrate is H-D-Val-Leu-Lys-AMC available from Bahcem. The assay buffer is 100 mM sodium...More data for this Ligand-Target Pair
Affinity DataKi: 750nMAssay Description:The assay uses baculovirus-expressed human cathepsin S and the boc-Val-Leu-Lys-AMC fluorescent substrate available from Bachem in a 384 well plate fo...More data for this Ligand-Target Pair
Affinity DataKi: 1.40E+3nMAssay Description:The enzyme is commercially available human cathepsin L (for example Calbiochem). The substrate is H-D-Val-Leu-Lys-AMC available from Bahcem. The assa...More data for this Ligand-Target Pair
Affinity DataKi: 1.40E+3nMAssay Description:The assay uses baculovirus-expressed human cathepsin S and the boc-Val-Leu-Lys-AMC fluorescent substrate available from Bachem in a 384 well plate fo...More data for this Ligand-Target Pair
Affinity DataKi: 1.40E+3nMAssay Description:The enzyme is commercially available human cathepsin L. The substrate is H-D-Val-Leu-Lys-AMC available from Bahcem. The assay buffer is 100 mM sodium...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:The assay uses baculovirus-expressed human cathepsin S and the boc-Val-Leu-Lys-AMC fluorescent substrate available from Bachem in a 384 well plate fo...More data for this Ligand-Target Pair
Affinity DataKi: 2.05E+4nMAssay Description:The assay uses baculovirus-expressed human cathepsin S and the boc-Val-Leu-Lys-AMC fluorescent substrate available from Bachem in a 384 well plate fo...More data for this Ligand-Target Pair
Affinity DataKi: 2.20E+4nMAssay Description:The assay uses baculovirus-expressed human cathepsin S and the boc-Val-Leu-Lys-AMC fluorescent substrate available from Bachem in a 384 well plate fo...More data for this Ligand-Target Pair
Affinity DataKi: 2.20E+4nMAssay Description:The assay uses baculovirus-expressed human cathepsin S and the boc-Val-Leu-Lys-AMC fluorescent substrate available from Bachem in a 384 well plate fo...More data for this Ligand-Target Pair