BDBM124450 US8759532, 107::US8759532, 187

SMILES O=C(c1nc2ccccc2[nH]1)c1ccc(Oc2ncccc2[C@@H]2CCOC2)cc1

InChI Key InChIKey=RLULHYKXDSLNFG-MRXNPFEDSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 124450   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM124450(US8759532, 107 | US8759532, 187)
Affinity DataIC50:  0.920nMT: 2°CAssay Description:To check the inhibition profile, 5 μL of serial diluted compounds were incubated with 5 μL of diluted PDE10 enzyme (BPS Bioscience, San Die...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM124450(US8759532, 107 | US8759532, 187)
Affinity DataIC50:  0.232nMT: 2°CAssay Description:To check the inhibition profile, 5 μL of serial diluted compounds were incubated with 5 μL of diluted PDE10 enzyme (BPS Bioscience, San Die...More data for this Ligand-Target Pair
In DepthDetails US Patent