BDBM125218 US8772481, 16

SMILES Cc1ccccc1-c1nncc2nc(Oc3ccc(F)cc3F)ccc12

InChI Key InChIKey=VXPNERZOGCAETM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 125218   

TargetMitogen-activated protein kinase 14(Human)
Amgen

US Patent
LigandPNGBDBM125218(US8772481, 16)
Affinity DataIC50:  0.200nMpH: 7.5Assay Description:Kinase reaction buffer for p38alpha HTRF assays consists of 50 mM Tris-pH 7.5, 5 mM MgCl2, 0.1 mg/mL BSA, 100 uM Na3VO4 and 0.5 mM DTT. HTRF Detectio...More data for this Ligand-Target Pair
In DepthDetails US Patent