BDBM12751 1-(3-carbamimidoylphenyl)-3-methyl-N-[4-(2-sulfamoylphenyl)phenyl]-1H-pyrazole-5-carboxamide::CHEMBL152854::CHEMBL37251::SN-429
SMILES Cc1cc(C(=O)Nc2ccc(cc2)-c2ccccc2S(N)(=O)=O)n(n1)-c1cccc(c1)C(N)=N
InChI Key InChIKey=APFKCRTWNKCURW-UHFFFAOYSA-N
Data 24 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 24 hits for monomerid = 12751
Affinity DataKi: 0.0130nMAssay Description:Tested in vitro for inhibition of human Coagulation factor XMore data for this Ligand-Target Pair
Affinity DataKi: 0.0130nMAssay Description:Tested for binding affinity against human Coagulation factor Xa (trypsin-like serine protease)More data for this Ligand-Target Pair
Affinity DataKi: 0.0130nM ΔG°: -14.7kcal/molepH: 7.0 T: 22°CAssay Description:Ki values were obtained from purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were determined ...More data for this Ligand-Target Pair
Affinity DataKi: 0.0130nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
Affinity DataKi: 0.0130nM ΔG°: -14.7kcal/molepH: 7.0 T: 22°CAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
Affinity DataKi: 0.0130nMAssay Description:Inhibition of human factor 10a using S-2765 as substrate after 30 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.0130nMAssay Description:Binding affinity against human coagulation factor XMore data for this Ligand-Target Pair
Affinity DataKi: 0.0130nMAssay Description:Inhibitory activity of the compound against Coagulation factor Xa (serine protease) was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 0.0300nMAssay Description:Binding affinity towards human trypsinMore data for this Ligand-Target Pair
Affinity DataKi: 0.0300nMAssay Description:In vitro activity against rabbit FXa.More data for this Ligand-Target Pair
Affinity DataKi: 0.0300nMAssay Description:Binding affinity towards Rabbit Coagulation factor X in a rabbit arterio-venous (A-V) shunt modelMore data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Tested for the binding affinity against trypsinMore data for this Ligand-Target Pair
Affinity DataKi: 16nM ΔG°: -10.5kcal/molepH: 7.0 T: 22°CAssay Description:Ki values were obtained from purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were determined ...More data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:In vitro activity against human trypsin.More data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Inhibition of human trypsin using S-2222 as substrate after 30 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Binding affinity towards human trypsinMore data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Tested in vitro for inhibition of human trypsinMore data for this Ligand-Target Pair
Affinity DataKi: 300nM ΔG°: -8.80kcal/molepH: 7.0 T: 22°CAssay Description:Ki values were obtained from purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were determined ...More data for this Ligand-Target Pair
Affinity DataKi: 300nMAssay Description:Binding affinity towards human thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 300nMAssay Description:Tested for the binding affinity against thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 300nMAssay Description:In vitro for inhibition of human thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 300nMAssay Description:Inhibition of human thrombin using S-2366 as substrate after 30 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataKi: 300nMAssay Description:In vitro activity against human thrombin.More data for this Ligand-Target Pair
Affinity DataKi: 1.90E+3nMAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair