BDBM129355 US8802686, 13

SMILES CS(=O)(=O)c1ccc(Nc2ncc(c(OCC#C)n2)C(F)(F)F)cc1

InChI Key InChIKey=PAICWQZQWHFNIR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 129355   

TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM129355(US8802686, 13)
Affinity DataIC50:  130nMpH: 8.0 T: 2°CAssay Description:CDK1/CycB (200 ng/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substances (0 and within the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM129355(US8802686, 13)
Affinity DataIC50:  610nMpH: 5.5 T: 2°CAssay Description:VEGF receptor tyrosine kinase (90 ng/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substance...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM129355(US8802686, 13)
Affinity DataIC50:  25nMpH: 8.0 T: 2°CAssay Description:CDK2/CycE (50 mg/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substances (0 uM, and within ...More data for this Ligand-Target Pair
In DepthDetails US Patent