BDBM129355 US8802686, 13
SMILES CS(=O)(=O)c1ccc(Nc2ncc(c(OCC#C)n2)C(F)(F)F)cc1
InChI Key InChIKey=PAICWQZQWHFNIR-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 129355
Affinity DataIC50: 130nMpH: 8.0 T: 2°CAssay Description:CDK1/CycB (200 ng/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substances (0 and within the...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Bayer Intellectual Property
US Patent
Bayer Intellectual Property
US Patent
Affinity DataIC50: 610nMpH: 5.5 T: 2°CAssay Description:VEGF receptor tyrosine kinase (90 ng/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substance...More data for this Ligand-Target Pair
Affinity DataIC50: 25nMpH: 8.0 T: 2°CAssay Description:CDK2/CycE (50 mg/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substances (0 uM, and within ...More data for this Ligand-Target Pair