BDBM129526 US8802673, 168::US8802673, 169

SMILES FC(F)(F)c1cnc(Nc2ccc(cc2Cl)C2CNCCO2)nc1

InChI Key InChIKey=FQWDUIMJRSIUPC-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 129526   

TargetTrace amine-associated receptor 7b(Rattus norvegicus (Rat))
Hoffmann-La Roche

US Patent
LigandPNGBDBM129526(US8802673, 168 | US8802673, 169)
Affinity DataKi:  6.5nM ΔG°:  -11.6kcal/molepH: 7.4 T: 2°CAssay Description:HEK-293 cells stably expressing mouse TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTrace amine-associated receptor 1(Mus musculus (Mouse))
Hoffmann-La Roche

US Patent
LigandPNGBDBM129526(US8802673, 168 | US8802673, 169)
Affinity DataKi:  7.70nM ΔG°:  -11.5kcal/molepH: 7.4 T: 2°CAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ina...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTrace amine-associated receptor 1(Mus musculus (Mouse))
Hoffmann-La Roche

US Patent
LigandPNGBDBM129526(US8802673, 168 | US8802673, 169)
Affinity DataKi:  24.3nM ΔG°:  -10.8kcal/molepH: 7.4 T: 2°CAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ina...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTrace amine-associated receptor 7b(Rattus norvegicus (Rat))
Hoffmann-La Roche

US Patent
LigandPNGBDBM129526(US8802673, 168 | US8802673, 169)
Affinity DataKi:  39.7nM ΔG°:  -10.5kcal/molepH: 7.4 T: 2°CAssay Description:HEK-293 cells stably expressing mouse TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...More data for this Ligand-Target Pair
In DepthDetails US Patent