BDBM12973 (2S)-2-({[(1R)-1-(4-bromophenyl)ethyl]carbamoyl}amino)-5-carbamimidamido-N-[(1S)-1-{[(2S)-5-carbamimidamido-1-oxo-1-(1,3-thiazol-2-yl)pentan-2-yl]carbamoyl}-2-methylpropyl]pentanamide::alpha-ketothiazole analogue 33

SMILES [#6]-[#6](-[#6])-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#7]-[#6@H](-[#6])-c1ccc(Br)cc1)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-c1nccs1

InChI Key InChIKey=WBAKUPSUHRKONA-MNAPGUCWSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 12973   

TargetCoagulation factor X(Homo sapiens (Human))
Daiichi Asubio Medical Research Laboratories

LigandPNGBDBM12973((2S)-2-({[(1R)-1-(4-bromophenyl)ethyl]carbamoyl}am...)
Affinity DataIC50:  250nMAssay Description:Enzyme peptidolytic activities were measured using a fluorogenic reporter group, 7-amido-4-methylcoumarin (AMC). Released AMC was measured at an emis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Daiichi Asubio Medical Research Laboratories

LigandPNGBDBM12973((2S)-2-({[(1R)-1-(4-bromophenyl)ethyl]carbamoyl}am...)
Affinity DataIC50:  7nMAssay Description:Enzyme peptidolytic activities were measured using a fluorogenic reporter group, 7-amido-4-methylcoumarin (AMC). Released AMC was measured at an emis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Daiichi Asubio Medical Research Laboratories

LigandPNGBDBM12973((2S)-2-({[(1R)-1-(4-bromophenyl)ethyl]carbamoyl}am...)
Affinity DataIC50:  440nMAssay Description:Enzyme peptidolytic activities were measured using a fluorogenic reporter group, 7-amido-4-methylcoumarin (AMC). Released AMC was measured at an emis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed