BDBM130503 US8822479, 37-1

SMILES CC(Cc1nc2n(ncc2c(=O)[nH]1)-c1ccccc1Cl)C(F)(F)F

InChI Key InChIKey=FFPXPXOAFQCNBS-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 130503   

TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Mouse)
Shaoxing University

Curated by ChEMBL

LigandBDBM130503(US8822479, 37-1)Copy SMILESCopy InChI

Affinity DataIC50:  55nMAssay Description:Displacement of [8-3H]-cGMP from recombinant mouse PDE9A expressed in baculovirus infected Sf9 insect cells incubated for 60 mins by scintillation pr...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoPurchasePC cidPC sidSimilars

In DepthDetails PubMed
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TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Boehringer Ingelheim International

US Patent

LigandBDBM130503(US8822479, 37-1)Copy SMILESCopy InChI

Affinity DataIC50:  60nMpH: 7.5Assay Description:The test substances are dissolved in 100% DMSO and serially diluted to determine their in vitro effect on PDE 9A. Typically, serial dilutions from 20...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sidSimilars

In DepthDetails US Patent

Copy BDB DOI