BDBM13055 CHEMBL283695::Compound 8::Topiramate Sulfamide Analogue 8::amino-N-{[(1R,2S,6S,9R)-4,4,11,11-tetramethyl-3,5,7,10,12-pentaoxatricyclo[7.3.0.0^{2,6}]dodecan-6-yl]methyl}sulfonamide

SMILES CC1(C)O[C@@H]2CO[C@@]3(CNS(N)(=O)=O)OC(C)(C)O[C@H]3[C@@H]2O1

InChI Key InChIKey=NQRKKQKMTGLNOZ-XBWDGYHZSA-N

Data  38 KI  2 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 13055   

TargetCarbonic anhydrase 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM13055(CHEMBL283695 | Compound 8 | Topiramate Sulfamide A...)
Affinity DataKi:  3.40E+5nMAssay Description:Inhibition of human carbonic anhydrase 2 by 4-NPA hydrolysis assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM13055(CHEMBL283695 | Compound 8 | Topiramate Sulfamide A...)
Affinity DataKd:  2.50E+4nMpH: 7.5Assay Description:Binding affinity to human carbonic anhydrase 2 in presence of 10 mM HEPES and 100 uM Na2SO4 at pH 7.5 by ThermoFluor methodMore data for this Ligand-Target Pair